There have been two massive studies completed by the National Eye Institute. The original study is called AREDS, which stands for Age Related Eye Disease Study. The second study is called AREDS 2. The important thing to know is that AREDS 2 is the latest and most up to date study on age related macular degeneration. These studies found that supplementing your diet with specific antioxidants, vitamins, and minerals can slow the progression of age related macular degeneration. Preserve Mac Forte Advanced is formulated based on aspects of the most up to date, AREDS 2, study.